As I read LWN today, I learned about Exaile, which is a Gtk+-based clone of Amarok. Amarok is the best Audio player I've ever used, and so people who are not using KDE and would rather not run Amarok which is KDE-based may wish to give Exaile a test drive. A caveat is that I haven't tried Exaile myself, nor intend to, because I am using Amarok on top of KDE and am pretty happy with this configuration.

The LWN report on the article where I found the link may also be of interest, but may still be subscribers-only content.